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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
4.24
Human Site:
S1027
Identified Species:
9.33
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
S1027
P
L
Y
G
S
L
S
S
F
P
K
P
A
P
R
Chimpanzee
Pan troglodytes
XP_526066
929
104074
R784
Q
E
S
P
K
M
P
R
K
E
P
L
P
C
P
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
S1061
P
P
P
P
L
P
D
S
A
I
F
L
S
P
S
Dog
Lupus familis
XP_542327
1264
138869
S1067
P
P
P
P
L
P
D
S
A
I
F
L
P
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
P1028
Y
G
S
V
S
S
F
P
K
L
V
P
R
K
E
Rat
Rattus norvegicus
P97573
1190
133575
P1027
Y
G
S
V
S
P
F
P
K
L
V
P
R
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
L874
F
F
P
P
L
R
P
L
T
P
S
L
I
R
S
Chicken
Gallus gallus
XP_422567
1182
133482
E1029
G
K
A
A
P
K
K
E
Q
D
Y
P
K
A
S
Frog
Xenopus laevis
Q6P4S2
1019
115278
Q874
E
K
D
E
T
V
A
Q
K
Q
L
K
H
P
Y
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
S1066
A
L
E
M
S
E
N
S
F
G
K
P
R
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
D1099
R
S
V
P
A
E
S
D
I
P
P
P
L
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
0
20
20
N.A.
13.3
13.3
N.A.
6.6
6.6
6.6
40
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
6.6
26.6
20
N.A.
13.3
13.3
N.A.
6.6
6.6
26.6
46.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
10
0
10
0
19
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
10
0
0
0
19
10
0
10
0
0
0
0
0
% D
% Glu:
10
10
10
10
0
19
0
10
0
10
0
0
0
0
19
% E
% Phe:
10
10
0
0
0
0
19
0
19
0
19
0
0
0
10
% F
% Gly:
10
19
0
10
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
19
0
0
10
0
0
% I
% Lys:
0
19
0
0
10
10
10
0
37
0
19
10
10
19
0
% K
% Leu:
0
19
0
0
28
10
0
10
0
19
10
37
10
0
0
% L
% Met:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
28
19
28
46
10
28
19
19
0
28
19
55
19
46
10
% P
% Gln:
10
0
0
0
0
0
0
10
10
10
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
10
0
10
0
0
0
0
28
10
10
% R
% Ser:
0
10
28
0
37
10
19
37
0
0
10
0
10
0
46
% S
% Thr:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
10
19
0
10
0
0
0
0
19
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
10
0
0
0
0
0
0
0
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _